Neurosurgeon — Neuropharmacology & Therapeutics

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What you'll learn:

Laying the Foundation - **Description:** This day will introduce the fundamental building blocks of the nervous system, the cells involved (neurons and glial cells), and the organization of the brain and spinal cord. You'll learn about basic brain regions and their functions, focusing on areas relevant to neuropharmacology. - **Resources/Activities:** - **Expected Outcomes:** Understand the basic structure and function of the nervous system, including the key cell types and overall organization of the brain. Be able to identify major brain regions.

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What you'll learn:

The Language of the Brain - **Description:** This day focuses on the neuron as the primary functional unit of the nervous system. You'll learn about neuron structure, action potentials, synaptic transmission (including presynaptic and postsynaptic events), neurotransmitters, and receptors. - **Resources/Activities:** - **Expected Outcomes:** Comprehend the structure and function of neurons, including the generation and propagation of action potentials, and how signals are transmitted between neurons at the synapse.

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Chemical Messengers - **Description:** This day delves into the world of neurotransmitters, exploring the major classes (e.g., amino acids, monoamines, peptides), their synthesis, release, inactivation, and receptor subtypes. Understanding receptors will be essential. - **Resources/Activities:** - **Expected Outcomes:** Understand the various classes of neurotransmitters, their synthesis, release, and breakdown. Be able to identify the major neurotransmitters and their associated receptors and functions.

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What you'll learn:

Drug Action and Interaction - **Description:** This day introduces fundamental pharmacological principles. You'll learn about drug absorption, distribution, metabolism, and excretion (ADME), as well as drug-receptor interactions, dose-response relationships, and pharmacokinetics/pharmacodynamics (PK/PD). - **Resources/Activities:** - **Expected Outcomes:** Understand the basic principles of how drugs interact with the body, including ADME processes, drug-receptor interactions, and dose-response relationships.

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What you'll learn:

- **Description:** Applying the knowledge from previous days, this day focuses on the specific application of pharmacology in the nervous system. You will be introduced to the different types of drugs and how they work within the brain including specific receptors and mechanisms - **Resources/Activities:** - **Expected Outcomes:** Understand how drugs affect neurotransmitter systems and the different potential targets for drug action.

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What you'll learn:

Examples and Applications - **Description:** Focusing on specific drugs used to treat neurological conditions. You'll learn about drugs for depression, anxiety, epilepsy, Parkinson's disease, and other conditions, including their mechanisms of action, therapeutic uses, side effects, and potential drug interactions. - **Resources/Activities:** - **Expected Outcomes:** Be able to recognize common neuropharmacological drugs and their primary therapeutic uses, mechanisms of action, and potential adverse effects.

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What you'll learn:

Advanced Concepts and Further Learning - **Description:** This day covers the blood-brain barrier (BBB), a critical element in neuropharmacology, and introduces ongoing research and future directions in drug development for neurological conditions. You'll also review and consolidate the week's learning. - **Resources/Activities:** - **Expected Outcomes:** Understand the role of the blood-brain barrier in drug delivery to the brain and have an awareness of current advances and future trends in neuropharmacology. Have a general understanding of the content covered over the previous 6 days.

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